Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force MicroscopyJoel Christian 1, Johannes W. Blumberg 2, Dimitri Probst 2, Cristina Lo Giudice 1, Sandra Sindt 3, Christine Selhuber-Unkel 3, Ulrich S. Schwarz 2, Elisabetta Ada Cavalcanti-Adam 1
1Department of Cellular Biophysics, Max Planck Institute for Medical Research, 2Institute for Theoretical Physics and BioQuant, Heidelberg University, 3Institute for Molecular Systems Engineering (IMSE), Heidelberg University
Near-UV lithography and traction force microscopy are combined to measure cellular forces on micropatterned hydrogels. The targeted light-induced release of single cells enables a high number of measurements on the same sample.
