Queen's University - Kingston, Ontario

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Detection of Neu1 Sialidase Activity in Regulating TOLL-like Receptor Activation

Schammim R. Amith^*1, Preethi Jayanth^*1, Trisha Finlay^*1, Susan Franchuk^*1, Alanna Gilmour^*1, Samar Abdulkhalek¹, Myron R. Szewczuk^*1

¹Department of Microbiology and Immunology, Queen's University - Kingston, Ontario

The sialidase assay is a simple technical approach that will elucidate novel molecular mechanism(s) of TLR sensors of microbial infections and involvement in inflammatory diseases at the receptor level on the cell surface of live macrophages.