Quantification of Atherosclerosis in MiceMonica Centa 1, Daniel F.J. Ketelhuth 1,2, Stephen Malin 1, Anton Gisterå 1
1Cardiovascular Medicine Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 2Department of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark (SDU)
Murine models of atherosclerosis are useful tools to investigate pathogenic pathways on a molecular level, but require standardized quantification of lesion development. This protocol describes an optimized method to determine lesion size in the major arterial vessels including the aortic root, aortic arch, and brachiocephalic artery.
