Results: Differentially Methylated INS DNA Measurements
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Conclusion
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The overall goal of this procedure is to measure differentially methylated preproinsulin DNA species in human serum as a biomarker of beta cell death. This method can help answer key questions in the diabetes field, such as, is beta cell death occ
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Islet β cell death precedes development of type 1 diabetes, and detecting this process may allow for early therapeutic intervention. Here, we provide a detailed description of how to measure differentially methylated INS DNA species in human serum as a biomarker of β cell death.