Results: Contraction Motion, Microelectrode Array, Patch Clamp Recordings and Ca2+ Imaging on hiPSC‐CMs
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Conclusion
Transcripción
Cardiac safety assessment is a crucial component during the drug development process. Human iPSC derived cardiomyocytes have proven to be a reliable, efficient, and human based model for pre-clinical cardiac safety assessment. We have established
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Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have emerged as a promising in vitro model for drug-induced cardiotoxicity screening and disease modeling. Here, we detail a protocol for measuring the contractility and electrophysiology of hiPSC-CMs.