Results: Histological Analysis of Orthotopic CRC-PDX Tumors and Therapeutic Efficacy of a Testing Drug
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Conclusion
Transcribir
This protocol describes the orthotopic implantation of patient-derived cancer cells in the cecum wall of immunodeficient mice. This model recapitulates advanced colorectal cancer metastatic disease. The orthotopic colorectal cancer model presented
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This protocol describes the orthotopic implantation of patient-derived cancer cells in the cecum wall of immunodeficient mice. The model recapitulates advanced colorectal cancer metastatic disease and allows for the evaluation of new therapeutic drugs in a clinically relevant scenario of lung and liver metastases.