Image Processing for Evaluating Bone Microarchitectural Parameters
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Collection of Microarchitectural Data from Reconstructed Images
4:16
Representative Results
5:44
Conclusion
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Osteoarthritis, or OA, is a degenerative joint disease that affects 32.5 million US adults. Often, OA symptoms appear only after the disease has become severe. The lack of disease-modifying drugs stems from a poor understanding of the mechanisms i
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Dunkin-Hartley guinea pigs are an established animal model for osteoarthritis research. Such studies may benefit from intra-articular injections for various reasons, including investigating novel agents or treating disease. We describe a methodology for intra-articular knee injections in Guinea pigs and subsequent micro-computed tomography analysis assessing arthritis-associated knee changes.