Philippe Soubeyran

Oligomerization and phosphorylation dependent regulation of ArgBP2 adaptive capabilities and associated functions.

Tropheryma whipplei, the agent of Whipple's disease, affects the early to late phagosome transition and survives in a Rab5- and Rab7-positive compartment.

Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins.

Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53.

Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination.

Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma.

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis.

Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells.

Pancreatic cancer chemo-resistance is driven by tumor phenotype rather than tumor genotype.

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.