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Queensland University of Technology (QUT)

3 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications
Felix M. Wunner 1, Onur Bas 1, Navid T. Saidy 1, Paul D. Dalton 2, Elena M. De-Juan Pardo 1, Dietmar W. Hutmacher 1,3,4
1ARC ITTC in Additive Biomanufacturing, Institute for Health and Biomedical Innovation (IHBI), Queensland University of Technology (QUT), 2Department for Functional Materials in Medicine and Dentistry and Bavarian Polymer Institute, University of Würzburg, 3Institute for Advanced Study, Technical University of Munich (TUM), 4George W Woodruff School of Mechanical Engineering, Georgia Institute of Technology

This protocol serves as a comprehensive guideline to fabricate scaffolds via electrospinning with polymer melts in a direct writing mode. We systematically outline the process and define the appropriate parameter settings for achieving targeted scaffold architectures.

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Bioengineering

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer
Matthew Lanaro *1, Jacob Skewes *1, Logan Spiers 1, Prasad K. Yarlagadda 1, Maria A. Woodruff 1
1Science and Engineering Faculty, Queensland University of Technology (QUT)

The aim of this work is to design and construct a reservoir-based melt extrusion three-dimensional printer made from open-source and low-cost components for applications in the biomedical and food printing industries.

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Bioengineering

An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion
Sebastian Eggert 1,2, Melanie Kahl 1,3, Ross Kent 1, Lukas Gaats 1, Nathalie Bock 1,3,4,5, Christoph Meinert 1,2, Dietmar W. Hutmacher 1,2,3,4,6
1Centre in Regenerative Medicine, Institute of Health and Biomedical Innovation, Queensland University of Technology, 2School of Mechanical, Medical and Process Engineering, Science and Engineering Faculty, Queensland University of Technology, 3School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, 4Australian Prostate Cancer Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, 5Translational Research Institute, Queensland University of Technology, 6ARC ITTC in Additive Biomanufacturing, Institute of Health and Biomedical Innovation, Queensland University of Technology

This protocol serves as a comprehensive tutorial for standardized and reproducible mixing of viscous materials with a novel open source automation technology. Detailed instructions are provided on the operation of a newly developed open source workstation, the usage of an open source protocol designer, and the validation and verification to identify reproducible mixtures.

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