Preparation of Drug-DMSO or Drug-Ethanol Stock Solutions and Drug Formulations
3:11
Solubility Testing
3:36
Results: Enhancement of Hydrophobic Compound Solubility in Aqueous Solution with Self-assembling Peptide and Amino Acid Solutions
4:16
Conclusion
Transcription
The overall goal of this method is to increase solubility of hydrophobic compounds in aqueous solution for potential delivery into clinical settings. This method addresses a key limitation in the medical field which is a lack of use of hydrophobic
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This protocol describes a clinically-applicable means of dissolving hydrophobic compounds in an aqueous environment using combinations of self-assembling peptide and amino acid solutions. Our method resolves a major limitation of hydrophobic therapeutics, which lack safe, efficient means of solubility and delivery methods into clinical settings.