Isolation of Infiltrating Immune Cells from Immunized Mice
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Results: Cell Immune Responses
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Conclusion
Transcription
Liver disease and cirrhosis are the sixth most common cause of death in adults between the ages of 25 and 64. Idiosyncratic DILI, sometimes referred to as drug-induced, autoimmune, or immune-mediated hepatitis, is the third most common cause of ac
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We describe an in vivo immunization, translational hepatitis model in BALB/c mice that can be utilized to study the pathogenesis of drug-induced autoimmune hepatitis including sex differences seen in this disease. We will describe how this model demonstrates reproducible analyses using in vivo and in vitro experimental techniques.