Sign In

Vifor Pharma Management Ltd

1 ARTICLES PUBLISHED IN JoVE

image

Medicine

Dynamic Light Scattering Analysis for the Determination of the Particle Size of Iron-Carbohydrate Complexes
Michael Burgert 1, Cintia Baptista Marques 2, Gerrit Borchard 2, Erik Philipp 1, Maria Wilhelm 1, Amy Alston 1, Reinaldo Digigow 1
1Vifor Pharma Group, Vifor Pharma Management Ltd, 2Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva

Dynamic light scattering (DLS) has emerged as a suitable assay for evaluating the particle size and distribution of intravenously administered iron-carbohydrate complexes. However, the protocols lack standardization and need to be modified for each iron-carbohydrate complex analyzed. The present protocol describes the application and special considerations for the analysis of iron sucrose.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved