Micro-CT Imaging and Morphometric Analysis of Mouse Neonatal BrainsJimena Barbeito-Andrés 1, Laura Andrini 2, Mariana Vallejo-Azar 1, Sara Seguel 3, Jay Devine 4, Benedikt Hallgrímsson 4, Paula Gonzalez 1
1Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos (ENyS, CONICET-UNAJ-HEC), 2Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 3Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, 4Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary
This study describes the steps for obtaining high-resolution images of neonatal mouse brains by combining micro-computed tomography (micro-CT) and a contrast agent in ex vivo samples. We describe basic morphometric analyses to quantify brain size and shape in these images.