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1 ARTICLES PUBLISHED IN JoVE

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Developmental Biology

Detection of DNA Double-Stranded Breaks in Mouse Oocytes
Chrysoula Zorzompokou 1,2, Marios Ipeirotis 1,2, Marios Kaisar Martzoukos 1, Petros Marangos 1,2
1Department of Biological Applications and Technology, University of Ioannina, 2Biomedical Research Institute, Foundation for Research and Technology

Maintaining oocyte genome integrity is necessary to ensure the genetic fidelity in the resulting embryo. Here, we present an accurate protocol for detecting DNA double-strand breaks in mammalian female germ cells.

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