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Mexico Children's Hospital

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Rapid and Efficient Enrichment of Mouse Spinal Cord Microglia
Claudia I Gutiérrez-Román 1,2, María E Meléndez Camargo 2, Cuauhtémoc C García Rojas 3, Miguel Jimenez Olvera 4, Sandra H Gutiérrez Román 5, Oscar Medina-Contreras 1
1Epidemiology, Endocrinology & Nutrition, Mexico Children's Hospital, 2Pharmacy Department, National School of Biological Sciences, National Polytechnic Institute, 3Graduate Department, Dr. Eduardo Liceaga General Hospital of Mexico, 4Pain Clinic and Palliative Care, Dr. Eduardo Liceaga General Hospital of Mexico, 5General Surgery Service, Metropolitan Angeles Hospital

Microglia are regarded as some of the most versatile cells in the body, capable of morphological and functional adaptation. Their heterogeneity and multifunctionality enable the maintenance of brain homeostasis, while also being linked to various neurological pathologies. Here, a technique for purifying spinal cord microglia is described.

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