Shenzhen Zhongshan Urology Hospital

1 ARTICLES PUBLISHED IN JoVE

Biology

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Cong Chen¹, Chunyu Huang^1,2, Yaya Wu¹, Zhihong Li¹, Shuyi Yu¹, Xiaoyan Chen¹, Ruochun Lian¹, Rong Lin¹, Lianghui Diao^1,2, Yong Zeng^1,2, Yuye Li^1,2

¹Shenzhen Key Laboratory of Reproductive Immunology for Peri-implantation, Shenzhen Zhongshan Institute for Reproduction and Genetics, Fertility Center, Shenzhen Zhongshan Urology Hospital, ²Shenzhen Jinxin Medical Technology Innovation Center, Co., Ltd.

Here, a digital immunohistochemistry image analysis platform was developed and validated to quantitatively analyze the endometrial immune cells of patients with recurrent miscarriages in the window of implantation.