<p class="jove_content">In this protocol, we describe the full process of establishing a pathology-relevant model for age-related macular degeneration (AMD) in primary mouse retinal pigment epithelial (RPE) cells using Alu RNA transfection.</p>

alu-rna-transfected-primary-mouse-retinal-pigment-epithelium

Alu RNA-transfected Primary Mouse Retinal Pigment Epithelium: A Pathologically Relevant In Vitro Model for Age-related Macular Degeneration

Age-related macular degeneration (AMD), particularly non-exudative AMD, requires experimental models that better replicate human pathology. Current in ...

<p class="jove_content">This study provides a detailed protocol for the efficient cryopreservation of human stem cell-derived retinal pigment epithelial cells.</p>

cryopreservation-human-embryonic-stem-cell-derived-retinal-pigment

Cryopreservation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells at the Optimal Stage

Retinal pigment epithelial&#160;(RPE) cells derived from human embryonic stem cells (hESCs) are superior cell sources for cell replacement therapy in ...

Institution - Shanghai Key Laboratory of Ocular Fundus Diseases

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