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1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock
Lars R. Lofgren 1, Guillaume L. Hoareau 2,3, Kai Kuck 1,4, Natalie A. Silverton 4,5
1Department of Biomedical Engineering, University of Utah, 2Department of Emergency Medicine, University of Utah, 3Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, 4Department of Anesthesiology, University of Utah, 5Geriatric Research, Education, and Clinical Centre, VAMC

Presented here is a protocol to measure renal oxygenation in the medulla and noninvasive urine oxygen partial pressure in a hemorrhagic shock porcine model to establish urine oxygen partial pressure as an early indicator of acute kidney injury (AKI) and a novel resuscitative endpoint.

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