University Medical Center Mannheim, Medical Faculty of the University of Heidelberg

1 ARTICLES PUBLISHED IN JoVE

Medicine

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications

Alexander Studier-Fischer^1,2,3,4, Berkin Özdemir^1,3,4, Karl-Friedrich Kowalewski^2,3,4, Caelan Max Haney^2,3,4,5, Maurice Stephan Michel^2,3,4, Gabriel Alexander Salg¹, Franck Billmann¹

¹Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, ²Department of Urology and Urosurgery, University Medical Center Mannheim, Medical Faculty of the University of Heidelberg, ³Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, ⁴DKFZ Hector Cancer Institute, University Medical Center Mannheim, ⁵Department of Urology, University Hospital Leipzig

Here we introduce a standardized procedure for endotracheal intubation via tracheotomy followed by thoracotomy in rats, aimed at enhancing the precision and reproducibility of non-survival applications requiring invasive ventilation and exposure of thoracic organs in in vivo rat models.