Sign In

Fondazione Policlinico Universitario ‘A. Gemelli’ - IRCCS

1 ARTICLES PUBLISHED IN JoVE

image

Cancer Research

Co-Culture In Vitro Systems to Reproduce the Cancer-Immunity Cycle
Nicoletta Manduca *1, Ester Maccafeo *1, Adele De Ninno 2, Antonella Sistigu 1,3, Martina Musella 1
1Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, 2CNR Institute for Photonics and Nanotechnology, 3Fondazione Policlinico Universitario ‘A. Gemelli’ - IRCCS

Here, we detail a simple, fast, and reliable multiparametric flow cytometry- and tumor-on-a-chip-assisted protocol to monitor and characterize the steps constituting the cancer-immunity cycle. Indeed, a thorough understanding of the interplays between cancer and immune cells provides critical insights to outsmart tumors and guide clinical care.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved