Studying Orthodontic Tooth Movement in MiceJosé Alcides Almeida de Arruda 1, João Pacheco Colares 2, Mariana de Souza Santos 3, Victor Zanetti Drumond 4, Talita Martins 5, Carolina Bosso André 2, Flávio Almeida Amaral 6, Ildeu Andrade Jr. 7, Tarcília Aparecida Silva 8, Soraia Macari 2
1Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, 2Department of Restorative Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, 3Department of Physiology and Biophysics, Biological Science Institute, Universidade Federal de Minas Gerais, 4Private Clinic, 5Department of Metallurgical and Materials Engineering, School of Engineering, Universidade Federal de Minas Gerais, 6Laboratory of Immunopharmacology, Department of Biochemistry and Immunology, Biological Science Institute, Universidade Federal de Minas Gerais, 7Department of Orthodontics, School of Dental Medicine, University of Pittsburgh, 8Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais
Here, we present a protocol for studying orthodontic tooth movement (OTM), serving as a suitable model for investigating the mechanisms of bone adaptation, root resorption, and the response of bone cells to mechanical stimuli. This comprehensive guide provides detailed information on the OTM model, micro-computed tomography acquisition, and subsequent analysis.
