Alternative Strategy to Analyze In Vitro Cell Invasion of 3D CulturesNatalie Ap. Rodrigues Fernandes 1, Camyla Rodrigues Nascimento 1, Laura Andrea González Maldonado 1,2, Carlos Rossa Junior 1
1Department of Diagnosis and Surgery - São Paulo State University (UNESP), School of Dentistry, Araraquara, 2Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan
Invasion is a major biological phenomenon in the development and progression of cancer. This process is influenced by non-neoplastic cells and components of the tumor microenvironment. The purpose of this study is to describe an alternative method for analyzing tumor cell invasion in vitro using three-dimensional (3D) cultures.