JoVE Logo

Sign In

Keck Graduate Institute

1 ARTICLES PUBLISHED IN JoVE

image

Neuroscience

Full- versus Sub-Regional Quantification of Amyloid-Beta Load on Mouse Brain Sections
Yuu Ohno 1, Riley Murphy 2, Matthew Choi 3, Weijun Ou 4, Rachita K. Sumbria 4,5
1Henry E. Riggs School of Applied Life Sciences, Keck Graduate Institute, 2Crean College of Health and Behavioral Sciences, Chapman University, 3Keck Science Department, Claremont McKenna College, 4Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy, Chapman University, 5Department of Neurology, University of California, Irvine

The present protocol describes and compares the procedure to perform a full-region or sub-region of interest analysis of sagittal mouse brain sections to quantify amyloid-beta load in the APP/PS1 transgenic mouse model of Alzheimer's disease.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved