Pseudofracture: An Acute Peripheral Tissue Trauma ModelSophie S. Darwiche 1, Philipp Kobbe 2, Roman Pfeifer 2, Lauryn Kohut 1, Hans-Christoph Pape 2, Timothy Billiar 1
1Department of Surgery, University of Pittsburgh, 2Department of Orthopedic Surgery, University of Aachen Medical Center
Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.
