National Cancer Institute, National Institutes of Health

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice

Wei Shen¹, Wenqing Li¹, Julie A. Hixon¹, Caroline Andrews¹, Scott K. Durum¹

¹Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health

We describe here a transgenic reporter mouse model to visualize the IL-22-producing cells inside different mouse tissues. This method can be used to track the location of other cytokines or secretary proteins in the mouse.