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Pusan National University

3 ARTICLES PUBLISHED IN JoVE

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Chemistry

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
Youngkyu Han 1, Suk-kyun Ahn 2,3, Zhe Zhang 1,4, Gregory S. Smith 1, Changwoo Do 1
1Biology and Soft Matter Division, Neutron Science Directorate, Oak Ridge National Laboratory, 2Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, 3Department of Polymer Science and Engineering, Pusan National University, 4Jülich Center for Neutron Science, Forschungszentrum Jülich

A method for the functionalization of carbon nanotubes with structure-tunable polymeric encapsulation layers and structural characterization using small-angle neutron scattering is presented.

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Medicine

Assessing Neuroprotective Effects of Glycyrrhizae Radix et Rhizoma Extract Using a Transient Middle Cerebral Artery Occlusion Mouse Model
Se-Eun Lee *1, Chiyeon Lim *2, Minji Lee 1, Chang-Hyun Kim 2, Hyungwoo Kim 1, Byoungho Lee 3, Suin Cho 1
1School of Korean Medicine, Pusan National University, 2College of Medicine, Dongguk University, 3Kyunghee Naseul Korean Medicine Clinic

In this study, we modify an existing experimental method to obtain more reproducible results, by establishing a middle cerebral artery occlusion (MCAO) mouse model. Oral administration of Glycyrrhizae Radix et Rhizome (GR) methanol extract (GRex), following stroke induction, significantly decreased total infarction volume relative to the untreated control group.

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Behavior

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
Hyeonwi Son 1, Ju Hwan Yang 2, Hyun Joon Kim *1, Dong Kun Lee *3
1Department of Anatomy and Convergence Medical Sciences, Institute of Health Sciences, Bio Anti-aging Medical Research Center, Gyeongsang National University Medical School, 2Department of Biological Sciences, Pusan National University, 3Department of Physiology and Convergence Medical Sciences, Institute of Health Sciences, Gyeongsang National University Medical School

This article provides a simplified and standardized protocol for induction of depressive-like behavior in chronically immobilized mice by using a restrainer. In addition, behavior and physiological techniques to verify induction of depression are explained.

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