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university of Tabriz

3 ARTICLES PUBLISHED IN JoVE

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Neuroscience

A Protocol for Transcranial Photobiomodulation Therapy in Mice
Farzad Salehpour 1,2, Luis De Taboada 3, Paolo Cassano 4,5,6, Farzin Kamari 1, Javad Mahmoudi 1, Sohrab Ahmadi-Kandjani 7, Seyed Hossein Rasta 8,9,10, Saeed Sadigh-Eteghad 1
1Neurosciences Research Center, Tabriz University of Medical Sciences, 2ProNeuroLIGHT LLC, 3LiteCure LLC, 4Department of Psychiatry, Harvard Medical School, 5Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, 6Center for Anxiety and Traumatic Stress Disorders, Department of Psychiatry, Massachusetts General Hospital, 7Research Institute for Applied Physics and Astronomy, University of Tabriz, 8Department of Medical Physics, Tabriz University of Medical Sciences, 9Department of Medical Bioengineering, Tabriz University of Medical Sciences, 10School of Medical Sciences, University of Aberdeen

Photobiomodulation therapy is an innovative noninvasive modality for the treatment of a wide range of neurological and psychiatric disorders and can also improve healthy brain function. This protocol includes a step-by-step guide to performing brain photobiomodulation in mice by transcranial light delivery, which can be adapted for use in other laboratory rodents.

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Behavior

Back Mechanical Sensitivity Assessment in the Rat for Mechanistic Investigation of Chronic Back Pain
Hatef Khosravi 1,2, Nasim Eskandari 1,2, Benjamin Provencher 1,2, Thierry Paquette 1,2, Hugues Leblond 1,2, Emad Khalilzadeh 1,3, Mathieu Piché 1,2
1Department of Anatomy, Université du Québec à Trois-Rivières, 2CogNAC Research Group, Université du Québec à Trois-Rivières, 3Division of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz

To develop novel therapeutic interventions for the prevention and management of back pain, animal models are required to examine the mechanisms and effectiveness of these therapies from a translational perspective. The present protocol describes the BMS test, a standardized method to assess back mechanical sensitivity in the rat.

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JoVE Core

Microfluidic Device for the Separation of Non-Metastatic (MCF-7) and Non-Tumor (MCF-10A) Breast Cancer Cells Using AC Dielectrophoresis
Ateeq ur Rehman 1, Rahman S. Zabibah 2, Samira Kharratian 3, Adil Mustafa 4,5
1Department of Biomedical Engineering, Foundation University Islamabad, 2College of Medical Technology, The Islamic University Najaf, 3Faculty of Mechanical Engineering, University of Tabriz, 4Department of Engineering Mathematics, University of Bristol, 5School of Life Sciences, University of Warwick

Breast cancer cells exhibit different dielectric properties compared to non-tumor breast epithelial cells. It has been hypothesized that, based on this difference in dielectric properties, the two populations can be separated for immunotherapy purposes. To support this, we model a microfluidic device to sort MCF-7 and MCF-10A cells.

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