Swedish Medical Center

2 ARTICLES PUBLISHED IN JoVE

Biology

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope

Niloofar Rezvani¹, Andrei V. Blokhin¹, Emil Zeynalov¹, Marguerite T. Littleton-Kearney¹

¹Graduate School of Nursing, Uniformed Services University of the Health Sciences

The goal of this article is to demonstrate a method to optimize immunofluorescent detection of estrogen receptor-α (ERα) in rat pial arterial slices using a digital immunofluorescent microscope.

Medicine

Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema

Emil Zeynalov¹, Susan M. Jones¹, J. Paul Elliott²

¹Neurotrauma Research, Swedish Medical Center, ²Neurosurgery, Colorado Brain and Spine Institute

Our studies have revealed that the beneficial effects of conivaptan are dependent on the method of delivery after experimental stroke in mice. We have developed a research protocol for delivery of the receptor blocker via IV catheter on stroke-evoked brain edema formation in mice.