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University Medicine Greifswald

3 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Measurement of Antibody Effects on Cellular Function of Isolated Cardiomyocytes
Lars G. Eckerle 1, Stephan B. Felix 1, Lars R. Herda 1
1Department of Internal Medicine B, University Medicine Greifswald

The presented method offers a way to detect functional effective cardiotropic autoantibodies in the plasma of patients with dilated cardiomyopathy, irrespective of the specific antigen, by analysing the impact of isolated patient immunoglobulin on cellular shortening and intracellular calcium transients in isolated rat cardiomyocytes.

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Behavior

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
Lisa Voigt 1,4, Antje Ullrich 1,4, Ulrike Siewert-Markus 1,2,4, Marcus Dörr 3,4, Ulrich John 1,4, Sabina Ulbricht 1,4
1Institute of Social Medicine and Prevention, University Medicine Greifswald, 2Institute for Medical Psychology, University Medicine Greifswald, 3Department of Internal Medicine B, University Medicine Greifswald, 4partner site Greifswald, DZHK (German Centre for Cardiovascular Research)

This protocol describes a randomized controlled trial as a method to test the effect of a video demonstration on the intra-individual difference between self-reported and accelerometer-based moderate-to-vigorous physical activity.

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Neuroscience

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
Filip Niemann *1, Alireza Shababaie *1, Sven Paßmann 1, Steffen Riemann 1, Robert Malinowski 1, Harund Kocataş 1, Leonardo M. Caisachana Guevara 1,2, Mohamed Abdelmotaleb 1, Daria Antonenko 1, Felix Blankenburg 3,4, Rico Fischer 2, Gesa Hartwigsen 5,6, Shu-Chen Li 7,8, Michael A. Nitsche 9,10,11, Axel Thielscher 12,13, Dagmar Timmann 14, Anna Fromm 1, Dayana Hayek 1, Ann-Kathrin Hubert 1, Andrew K. Martin 15,16, Alexander Hunold 17, Agnes Flöel *1,18, Marcus Meinzer *1
1Department of Neurology, University Medicine Greifswald, 2Department of Psychology, University Medicine Greifswald, 3Berlin School of Mind and Brain, Humboldt Universität zu Berlin, 4Neurocomputation and Neuroimaging Unit, Freie Universität Berlin, 5Wilhelm-Wundt-Institute for Psychology, Cognitive and Biological Psychology, Leipzig University, 6Lise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, 7Lifespan Developmental Neuroscience, Faculty of Psychology, Technische Universität Dresden, 8Centre for Tactile Internet with Human-in-the-Loop, Technische Universität Dresden, 9Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors, 10German Centre for Mental Health (DZPG), 11Clinic of Psychiatry and Psychotherapy, Protestant Hospital of Bethel Foundation, University Hospital OWL, Bielefeld University, 12Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Amager and Hvidovre, 13Department of Health Technology, Technical University of Denmark, 14Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Essen University Hospital, 15Department of Psychology, University of Kent, 16Kent Medway Medical School, 17Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, 18German Center for Neurodegenerative Diseases (DZNE Site Greifswald)

This protocol describes the method of neuronavigated electrode placement for focal, transcranial direct current stimulation (tDCS) administered during functional magnetic resonance imaging (fMRI).

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