Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow CytometryLorea Iturri 1,2, Javier Saenz Coronilla 1, Yvan Lallemand 1, Elisa Gomez Perdiguero 1
1Department of Developmental and Stem Cell Biology, CNRS UMR3738, Department of Immunology, Institut Pasteur, 2Cellule Pasteur UPMC, University Pierre et Marie Curie
While infiltrating macrophages are continuously recruited to adult tissues from circulating precursors, resident macrophages seed their tissue during development, where they are maintained without further input from progenitors. The progenitors for resident macrophages were recently identified. Here, we present methods for the genetic fate mapping of the resident macrophage progenitors.