Sign In

University Hospital of Strasbourg

2 ARTICLES PUBLISHED IN JoVE

image

Medicine

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Guillaume Bierry 1,2, Sophie Lefevre 2,3, Jean-Louis Dietemann 1, François Jehl 2,3
1Department of Radiology, University Hospital of Strasbourg, 2EA 3432, University of Strasbourg, 3Department of Bacteriology, University Hospital of Strasbourg

We demonstrate how to perform macrophage MR imaging using ultrasmall superparamagnetic contrast agent (USPIO) in septic arthritis, allowing an initial and longitudinal in vivo non-invasive evaluation of macrophages infiltration and an assessment of therapy efficacy.

image

Cancer Research

Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions
Quentin Fuchs 1, Aurélie Batut 2, Mélanie Gleyzes 2, Jessica Rontard 2, Louise Miny 2, Margot Libralato 2, Janaina Vieira 2, Delphine Debis 2, Florian Larramendy 2, Thibault Honegger 2, Melissa Messe 1, Marina Pierrevelcin 1, Benoit Lhermitte 1,3, Monique Dontenwill 1, Natacha Entz-Werlé 1,4
1Team Tumoral signaling and therapeutic targets, UMR CNRS 7021 - Laboratory of Bioimaging and Pathologies, 2NETRI, 3Centre de Ressources Biologiques, Pathology department, University Hospital of Strasbourg, 4Pediatric Oncohematology unit, University Hospital of Strasbourg

Recent works uncover the neuronal impact on high-grade pediatric glioma (pHGG) cells and their reciprocal interactions. The present work shows the development of an in vitro model co-culturing pHGG cells and glutamatergic neurons and recorded their electrophysiological interactions to mimic those interactivities.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved