University of Witwatersrand

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Denise Lawrie^1,2, George Janossy², Maarten Roos³, Deborah K. Glencross^1,2

¹National Health Laboratory Services (NHLS-SA), ²Department of Molecular Medicine and Haematology, University of Witwatersrand, ³Lightcurve Films

Anti-retroviral therapy to treat HIV/AIDS is monitored in South Africa on a large scale. Flow cytometry is combined for haematology (CD45), immunology (CD4) and viral-load linked CD38 assay. Recorded at NHLS-SA laboratories, Johannesburg, these modern methods are cost-efficient with heightened local internal quality control, serving as role-models for resource-limited diagnostics.