Sanford-Burnham-Prebys Medical Discovery Institute at Lake Nona

2 ARTICLES PUBLISHED IN JoVE

Developmental Biology

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation

Zoltan Simandi^*1, Attila Horvath^*2, Peter Nagy¹, Laszlo Nagy^1,2,3

¹Sanford-Burnham-Prebys Medical Discovery Institute at Lake Nona, ²Department of Biochemistry and Molecular Biology, Research Center for Molecular Medicine, Medical and Health Science Center, University of Debrecen, ³MTA-DE “Lendulet” Immunogenomics Research Group, University of Debrecen

In this work we provide an experimental workflow of how active enhancers can be identified and experimentally validated.

Bioengineering

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Csaba Jenei¹, Laszlo Nagy¹, Reka Urbancsek¹, Daniel Czuriga¹, Zoltan Csanadi¹

¹Division of Cardiology, Department of Cardiology, Faculty of Medicine, University of Debrecen

The dimensions of the pulmonary veins (PV) are important parameters when planning pulmonary vein isolation. 2D transoesophageal echocardiography can only provide limited data about the PVs; however, 3D echocardiography can evaluate relevant diameters and areas of the PVs, as well as their spatial relationship to surrounding structures.