A Renal Denervation Approach to Prevent Inflammation and Fibrogenesis in Chronic Kidney DiseaseHee-Seong Jang 1, Mi Ra Noh 1, Jinu Kim 1,2,3, Babu J. Padanilam 1,4
1Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, 2Department of Anatomy, Jeju National University School of Medicine, 3Interdisciplinary Graduate Program in Advanced Convergence Technology & Science, Jeju National University, 4Internal Medicine, Section of Nephrology, University of Nebraska Medical Center
Described here is a protocol for renal denervation that is used to define the role of renal nerve-derived signaling in persistent renal tubular injury, inflammation, and fibrogenesis. It is focused on sympathetic nerve-mediated signaling.