Surgical Transplantation of Tumor Cells into the Spinal Cord of MiceXun Mingjuan *1,2,3, Lin Han *4,5, Yu Caiyuan 1,6,7, Pang Bo 4, Wang Yongzhi 4,5, Yan Jun 1,2,3
1Beijing Institute of Brain Disorders, Capital Medical University, 2Laboratory of Brain Disorders, Ministry of Science and Technology, Capital Medical University, 3Collaborative Innovation Center for Brain Disorders, Capital Medical University, 4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 5Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, 6State Key Laboratory of Quality Research in Chinese Medicines, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, 7Faculty of Agroforestry and Medicine, The Open University of China
The present protocol describes the development of a reproducible murine model of spinal cord glioma by injecting tumor cells into the intervertebral space, offering a more effective and less invasive approach for research and therapeutic development.
