Functional and Physiological Methods of Evaluating Median Nerve Regeneration in the RatDiogo Casal *1,2, Eduarda Mota-Silva *3, Inês Iria 4,5, Diogo Pais 1, Ana Farinho 6, Sara Alves 7, Cláudia Pen 7, Luís Mascarenhas-Lemos 7, José Ferreira-Silva 7, Mário Ferraz-Oliveira 7, Valentina Vassilenko 3, Paula A. Videira 4,5, João Goyri-O'Neill 1
1Anatomy Department, NOVA Medical School, 2Plastic and Reconstructive Surgery Department and Burn Unit, Centro Hospitalar de Lisboa Central, 3Physics Department, Faculty of Sciences and Technology, LIBPhys, 4Glycoimmunology, CEDOC, NOVA Medical School, 5UCIBIO, Life Sciences Department, Faculty of Sciences and Technology, Universidade NOVA de Lisboa, 6Tissue Repair Unit, CEDOC, NOVA Medical School, 7Pathology Department, Centro Hospitalar de Lisboa Central
Presented is a protocol to produce different types of median nerve (MN) lesions and repair in the rat. Additionally, the protocol shows how to evaluate the functional recovery of the nerve using several noninvasive behavioral tests and physiological measurements.