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Beijing Institute of Precision Mechatronics and Controls

4 ARTICLES PUBLISHED IN JoVE

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Engineering

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation
Jonathan A. Kopechek 1, Peng Zhang 1, Mark T. Burgess 1, Tyrone M. Porter 1
1Department of Mechanical Engineering, Boston University

Phase-shift nanoemulsions (PSNE) can be vaporized using high intensity focused ultrasound to enhance localized heating and improve thermal ablation in tumors. In this report, the preparation of stable PSNE with a narrow size distribution is described. Furthermore, the impact of vaporized PSNE on ultrasound-mediated ablation is demonstrated in tissue-mimicking phantoms.

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Biology

Partial Bile Duct Ligation in the Mouse: A Controlled Model of Localized Obstructive Cholestasis
Shinichiro Yokota 1,2, Yoshihiro Ono 2, Toshimasa Nakao 2, Peng Zhang 3, George K. Michalopoulos 4,5, Zahida Khan 3,4,5,6
1Department of Surgery, Jichi Medical University, 2Department of Surgery, University of Pittsburgh School of Medicine, 3Department of Pediatrics, University of Pittsburgh School of Medicine, 4Department of Pathology, University of Pittsburgh School of Medicine, 5Pittsburgh Liver Research Center, University of Pittsburgh, 6McGowan Institute for Regenerative Medicine, University of Pittsburgh

Here, we present partial bile duct ligation as a surgical model of liver injury and regeneration in rodents.

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Genetics

Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
Jinxia Shi 1, Yijuan Jia 1, Di Fang 1, Shidan He 1, Peng Zhang 1,2, Yushuang Guo 3, Yongli Qiao 1
1Shanghai Key Laboratory of Plant Molecular Sciences, College of Life Sciences, Shanghai Normal University, 2College of Agriculture, Yangtze University, 3Laboratory of Molecular Genetics, China National Tobacco Corporation, Guizhou Institute of Tobacco Science

Here, we present a modified screening method that can be extensively used to quickly screen RNA silencing suppressors in plant pathogens.

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JoVE Core

A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump
Xu Han 1, Peng Zhang 2, Tatiana Minav 3, Yongling Fu 1, Jian Fu 1
1School of Mechanical Engineering and Automation, Beihang University, 2Beijing Institute of Precision Mechatronics and Controls, 3Innovative Hydraulics and Automation, Tampere University

A simulation model specifically supporting the preliminary design of an electro-variable displacement pump (EVDP) is developed and partially verified by experiments. The control performance, life, reliability, etc., can all be evaluated using the proposed model, which covers the main performance requirements under the EVDP preliminary design task.

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