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University of Colima

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Targeting of Deep Brain Structures with Microinjections for Delivery of Drugs, Viral Vectors, or Cell Transplants
Oscar Gonzalez-Perez 1, Hugo Guerrero-Cazares 2, Alfredo Quiñones-Hinojosa 2
1 Neuroscience Lab/ Fac. Psicologia, University of Colima, 2Department of Neurosurgery, Johns Hopkins University

In this article, we show a method to make glass capillary needles with a 50-μm lumen. This technique significantly reduces the brain damage, minimizes passive diffusion of drugs and allows a precise targeting into the rodent brain.

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