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Fritz Lipmann Institute

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves
Alexander Schulz 1, Christian Walther 2, Helen Morrison 1, Reinhard Bauer 3
1Leibniz Institute for Age Research, Fritz Lipmann Institute, 2Friedrich Schiller University Jena, 3Institute of Molecular Cell Biology & Center for Sepsis Control and Care (CSCC) Jena University Hospital, Friedrich Schiller University Jena

Measurements of nerve conduction properties in vivo exemplify a powerful tool to characterize various animal models of neuromuscular diseases. Here, we present an easy and reliable protocol by which electrophysiological analysis on sciatic nerves of anesthetized mice can be performed.

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