JoVE Logo

Sign In

MIT

3 ARTICLES PUBLISHED IN JoVE

image

Engineering

Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles
Xi Wei 1,2, Abeer Syed 1, Pan Mao 3, Jongyoon Han 4, Yong-Ak Song 1,2
1Division of Engineering, New York University Abu Dhabi (NYUAD), 2Department of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, 3Newomics, Inc., 4Department of Electrical Engineering and Computer Science, Department of Biological Engineering, MIT

We propose a simple self-assembly technique of silica colloidal nanoparticles to create a nanofluidic junction between two microchannels in polydimethylsiloxane (PDMS). Using this technique, a nanoporous bead membrane with a pore size down to ~45 nm was built inside a microchannel and applied to electrokinetic preconcentration of DNA samples.

image

Immunology and Infection

Label-free Neutrophil Enrichment from Patient-derived Airway Secretion Using Closed-loop Inertial Microfluidics
Hyunryul Ryu 1, Kyungyong Choi 1,2, Yanyan Qu 3, Taehong Kwon 1,2, Janet S. Lee 3,5, Jongyoon Han 1,2,4
1Research Laboratory of Electronics, Massachusetts Institute of Technology, 2Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, 3Department of Medicine, University of Pittsburgh, 4Department of Biological Engineering, Massachusetts Institute of Technology, 5Vascular Medicine Institute, University of Pittsburgh

In this research, we demonstrate a label-free neutrophil separation method from clinical airway secretions using closed-loop operation of spiral inertial microfluidics. The proposed method would expand the clinical in vitro assays for various respiratory diseases.

image

Engineering

Design and Fabrication of an Optical Fiber Made of Water
Mark L. Douvidzon 1, Shai Maayani 2, Leopoldo L. Martin 3, Tal Carmon 4
1Department of Nanoscience and Nanotechnology, Russell Berrie Nanotechnology Institute (RBNI), Technion - Israel Institute of Technology, 2Department of Material Sciences and Engineering, MIT, 3Centro de Tecnologia Nanofotónica, Universitat Politècnica de València, 4Department of Mechanical Engineering, Technion - Israel Institute of Technology

This protocol describes the design and manufacture of a water bridge and its activation as a water fiber. The experiment demonstrates that capillary resonances of the water fiber modulate its optical transmission.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved