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University of Illinois at Urbana–Champaign

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces
Kerim B. Kaylan 1, Andreas P. Kourouklis 1, Gregory H. Underhill 1
1Department of Bioengineering, University of Illinois at Urbana–Champaign

Cell differentiation is regulated by a host of microenvironmental factors, including both matrix composition and substrate material properties. We describe here a technique utilizing cell microarrays in conjunction with traction force microscopy to evaluate both cell differentiation and biomechanical cell–substrate interactions as a function of microenvironmental context.

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