Université de Reims Champagne Ardenne

1 ARTICLES PUBLISHED IN JoVE

Chemistry

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes

Tarun Kumar^1,2, Amira Ben Hassine¹, Agathe Martinez¹, Dominique Harakat¹, Sylviane Chevreux¹, Fabien Massicot¹, Marc Taillefer², Jean-Bernard Behr¹, Jean-Luc Vasse¹, Florian Jaroschik^1,2

¹Institut de Chimie Moléculaire de Reims UMR 7312, Université de Reims Champagne Ardenne, ²Institut Charles Gerhardt Montpellier UMR 5253, Ecole Nationale Supérieure de Chimie de Montpellier

This protocol describes the preparation of elemental lanthanides under inert atmosphere and their application in a selective C-F activation process involving trifluoromethylated benzofulvenes.