Unidad de Animalario del Centro de Investigación Príncipe Felipe (CIPF)

1 ARTICLES PUBLISHED IN JoVE

Biology

Noninvasive Monitoring of Lesion Size in a Heterologous Mouse Model of Endometriosis

Jessica Martinez¹, Viviana Bisbal², Nerea Marin², Antonio Cano^1,3,4, Raul Gómez¹

¹Instituto de Investigación Sanitaria, ²Unidad de Animalario del Centro de Investigación Príncipe Felipe (CIPF), ³Departamento de Pediatría, Obstetricia y Ginecología, Universidad de Valencia, ⁴Servicio de Obstetricia y Ginecología, Hospital Clínico Universitario de Valencia

Here, we present a protocol for live-imaging of fluorescently labeled human endometrial fragments grafted in mice. The method allows studying the effects of drugs of choice on endometriotic lesion size through monitoring and quantification of fluorescence emitted by the fluorescent reporter on real time