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JST PRESTO

2 ARTICLES PUBLISHED IN JoVE

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Engineering

A Polymer-based Piezoelectric Vibration Energy Harvester with a 3D Meshed-Core Structure
Takuya Tsukamoto 1, Yohei Umino 1, Kotaro Hashikura 1, Sachie Shiomi 1, Kou Yamada 1, Takaaki Suzuki 1,2
1Gunma University, 2JST PRESTO

In this study, we fabricated a flexible 3D mesh structure and applied it to the elastic layer of a bimorph cantilever-type vibration energy harvester for the purpose of lowering resonance frequency and increasing output power.

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Biochemistry

Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device
Masatoshi Maeki 1,2, Yuto Okada 3, Shuya Uno 3, Ayuka Niwa 3, Akihiko Ishida 1, Hirofumi Tani 1, Manabu Tokeshi 1
1Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, 2JST PRESTO, 3Graduate School of Chemical Sciences and Engineering, Hokkaido University

Microfluidic-based lipid nanoparticle (LNP) production methods have attracted attention in drug delivery systems (DDSs), including RNA delivery. This protocol describes the fabrication, LNP (siRNA-loaded LNP) production, and LNP evaluation processes using our original microfluidic device named iLiNP.

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