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Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran

1 ARTICLES PUBLISHED IN JoVE

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Biochemistry

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils
Ramin Zadali 1, Ebrahim Rostampour Ghareghozloo *1, Mohammad Ramezani *1, Vahid Hassani *1, Yasin Rafiei *1, Shiva Mohammadi Chiyaneh 1, Ali Akbar Meratan 1
1Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran

Provided here is a protocol for investigating the interactions between native form, prefibrillar, and mature amyloid fibrils of different peptides and proteins with mitochondria isolated from different tissues and various areas of the brain.

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