Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid FibrilsRamin Zadali 1, Ebrahim Rostampour Ghareghozloo *1, Mohammad Ramezani *1, Vahid Hassani *1, Yasin Rafiei *1, Shiva Mohammadi Chiyaneh 1, Ali Akbar Meratan 1
1Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran
Provided here is a protocol for investigating the interactions between native form, prefibrillar, and mature amyloid fibrils of different peptides and proteins with mitochondria isolated from different tissues and various areas of the brain.