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The Hebrew University-Hadassah Medical School

2 ARTICLES PUBLISHED IN JoVE

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Cancer Research

Monitoring Breast Cancer Growth and Metastatic Colony Formation in Mice using Bioluminescence
Balakrishnan Solaimuthu 1, Arata Hayashi 1, Anees Khatib 1, Yoav D. Shaul 1
1Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School

Here, we describe a noninvasive monitoring method involving luciferase and green fluorescent protein expression in various breast cancer cell lines. This protocol provides a technique to monitor tumor formation and metastatic colonization in real time in mice.

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Biology

Simple Continuous Glucose Monitoring in Freely Moving Mice
Doron Kleiman 1, Mika Littor 1,2, Mahmoud Nawas 3, Rachel Ben-Haroush Schyr 1, Danny Ben-Zvi 1
1Department of Developmental Biology and Cancer Research, Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, 2Department of Military Medicine and “Tzameret”, Faculty of Medicine, Hebrew University of Jerusalem, and Medical Corps, Israel Defense Forces, 3Department of Surgery, Hadassah Medical Center-Ein Kerem Campus

Here, we describe a simple method to implant a commercial continuous glucose monitor designed for patients onto mice and provide the scripts to analyze the results.

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