CD Spectroscopy to Study DNA-Protein InteractionsVijendra Arya 1, Anindita Dutta 1, Rohini Muthuswami 1
1Jawaharlal Nehru University New Delhi
The interaction of an ATP-dependent chromatin remodeler with a DNA ligand is described using CD spectroscopy. The induced conformational changes on a gene promoter analyzed by the peaks generated can be used to understand the mechanism of transcriptional regulation.