Multi-Stream Perfusion Bioreactor Integrated with Outlet Fractionation for Dynamic Cell CulturePatrick Erickson 1, Aneesha Doshi 2, Gunjan Jetley 2, Param Amin 2, Aamena Mejevdiwala 2, Ashna Patel 2, Raphaela Bento 2, Biju Parekkadan 2,3
1Department of Chemical and Biochemical Engineering, Rutgers University, 2Department of Biomedical Engineering, Rutgers University, 3Department of Medicine, Rutgers Biomedical Health Sciences
This paper presents a method to construct and operate a low-cost, multichannel perfusion cell culture system for measuring the dynamics of secretion and absorption rates of solutes in cellular processes. The system can also expose cells to dynamic stimulus profiles.
