In Vitro Myelination of Peripheral Axons in a Coculture of Rat Dorsal Root Ganglion Explants and Schwann CellsAlina Blusch 1, Melissa Sgodzai 1, Niklas Rilke 1, Jeremias Motte 1, Jennifer König 1, Kalliopi Pitarokoili 1, Thomas Grüter 1
1Department of Neurology, Ruhr-University Bochum, St. Josef Hospital
In the coculture system of dorsal root ganglia and Schwann cells, myelination of the peripheral nervous system can be studied. This model provides experimental opportunities to observe and quantify peripheral myelination and to study the effects of compounds of interest on the myelin sheath.