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Biochemistry

High-Throughput Protein Crystallization via Microdialysis
Tristan O. C. Kwan 1, Amy E. Danson 1, Pascelle Draper 2, Paul Reardon 2, Isabel Moraes 1
1National Physical Laboratory, 2SWISSCI LTD

The presented protocol describes a straightforward approach for screening protein crystallization conditions and crystal growth using a 96-well high-throughput dialysis plate. The use of dialyzer tubes for the large-scale growth of microcrystals is also demonstrated for serial crystallography and MicroED applications.

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